Psychological characteristics and fatal ischaemic heart disease

Psychological characteristics and fatal ischaemic heart disease.

OBJECTIVE To determine the relation between psychological characteristics and subsequent fatal ischaemic heart disease (IHD) events. DESIGN Prospective study of participants in the Northwick Park heart study (NPHS) recruited between 1972 and 1978 and followed up for fatal events until 1997. SETTING Three occupational groups in north west London. SUBJECTS 1408 white men without a history o...

Psychological influences on cancer and ischaemic heart disease.

Metabolomics and ischaemic heart disease.

Ischaemic heart disease accounts for nearly half of the global cardiovascular disease burden. Aetiologies relating to heart disease are complex, but dyslipidaemia, oxidative stress and inflammation are cardinal features. Despite preventative measures and advancements in treatment regimens with lipid-lowering agents, the high prevalence of heart disease and the residual risk of recurrent events ...

Thrombosis and ischaemic heart disease.

The overwhelming dominance of the lipid hypothesis for atheroma has obscured the compelling evidence-some of it of many years standing' but some that is more recent2 3 -that both platelets and the coagulation system also contribute to the lesion. There is much epidemiological evidence4 5 of some other process besides atherogenesis to account for the clinical manifestations of coronary artery di...

Ischaemic heart disease.

There can be no truly objective frequency estimate of the susceptibility of the population to ischaemic heart disease: everybody has some degree of susceptibility. The disease kills 1 in 4 of the population, and 1 man in 10 dies of ischaemic heart disease before 65 years of age. The major burden is mortality, though there is often some degree of impairment among survivors of acute attacks. It i...